MCL Project Highlight

Principal Investigator: Gloria Elliott, PhD

Department: Mechanical Engineering & Engineering Science

Title: The development and application of environmentally friendly organic salts for a range of energy and biomedical applications

Summary: In the last two decades there has been considerable growth in the development of novel low melting point organic salts, called ‘ionic liquids’, for a range of practical applications. The ability to tailor these compounds to achieve desired physical properties has enabled researchers to ‘design for task’. Dr. Gloria Elliott has been developing the design rules for bio-compatibility, protein stability, membrane penetration, and most recently CO2 absorption, and enhanced heat transfer.  Applications of this work include the development of stabilizing formulations for storage and delivery of the protein therapeutic Interleukin-2, the absorption and storage of CO2 from stack emissions, and enhanced storage and heat transfer in solar thermal energy capture devices. The development of novel working fluids for waste heat recovery cycles is also of interest. Use of the thermal analysis equipment in the materials characterization laboratory enables continued development of the understanding of the structure-property relationships as they pertain to the above mentioned applications.

Recent Publications:

Lindong Weng, Gloria D. Elliott, Local Minimum in Fragility for Trehalose/Glycerol Mixtures: Implications for Biopharmaceutical Stabilization, Journal of Physical Chemistry: B, 2015, 119(22), 6820-6827.

Lindong Weng, Gloria D. Elliott, Distinctly Different Glass Transition Behaviors of Trehalose Mixed with Na2HPO4 or NaH2PO4: Evidence for its Molecular Origin, Pharmaceutical Research, 2015, 32(7), 2217-2228.

Lindong Weng, Gloria D. Elliott, Determination of the relaxation characteristics of sugar glasses embedded in microfiber substrates, Mat. Sci. Eng. C, 2014, 44, 422-429.